In order to more accurately discover the cause of drug resistance in tumor treatment, and to provide a new basis for precise treatment. Therefore, based on the umbrella theory of precision medicine, we carried out this single-center, prospective, and observational study to include patients with liver metastases from colorectal cancer. By combining genome, transcriptome, and proteomic sequencing data, we established a basis for colorectal cancer liver Transfer the multi-omics data of the sample, describe the reason for the resistance of the first-line treatment, and search for new therapeutic targets.
Study Type
OBSERVATIONAL
Enrollment
200
Use multi-omics to analyze
Objective response rate
Refers to the proportion of patients whose tumors have shrunk to a certain amount and maintained for a certain period of time, including complete remission (CR) and partial remission (PR) cases
Time frame: 1 year
progression-free survival
Refers to the date from initial diagnosis to tumor progression
Time frame: 1 year
Overall survival
Refers to the date from initial diagnosis to last follow-up or death date
Time frame: 3 years
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