Osteosarcopenia and Exercise

Sisli Hamidiye Etfal Training and Research Hospital27 enrolled

Overview

The purpose of this study is to assess the efficacy of combination of aerobic and resistive exercise on activities of daily living and risk of fall in osteosarcopenic patients

After being informed about the study and potential risk, all patients giving written informed consent will undergo study entry. to begin with: assessment with bioelectrical body composition analyzer and first exercise and assessment clinical scales 1th month: assessment with bioelectrical body composition analyzer and assessment clinical scales 3th month: assessment with bioelectrical body composition analyzer and assessment clinical scales

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Sarcopenia Osteoporosis, Osteopenia

Interventions

exerciseOTHER

the combination of aerobic and resistive exercise, three time a week

Eligibility

Sex: ALLMin age: 70 YearsMax age: 91 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Over 70 years of age * Clinical diagnosis of osteoporosis or osteopenia * Independent mobilization * Walking speed \< 0.8 m / sec * Grip strength \< 20 kg for women, \< 30 kg for men Exclusion Criteria: * Uncontrolled hypertension (systolic blood pressure\> 200 mmHg, diastolic blood pressure\> 110 mmHg) * Uncontrolled diabetes mellitus * Stroke, hip fracture, knee and hip arthroplasty, spinal surgery in the last 6 months * Severe cardiac arrhythmia * Myocardial infarction in the last 6 months * Severe dementia and difficulties in cooperation * Cardiac pacemaker * Dialysis * Acute infection * Severe edema * Malignancy patients * Severe anemia (Hgb \<8 mg / dl)

Locations (1)

Şişli Hamidiye Etfal Training and Research Hospital

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Change from Baseline on Skeletal Muscle Mass Measurement at month 3

Assessment with bioelectrical body composition analyzer male: SMI\<9,2 kg/m2 female: SMI\<7,4 kg/m2

Time frame: Baseline and Month 3

Change from Baseline on Skeletal Muscle Mass Measurement at month 1

Assessment with bioelectrical body composition analyzer male: SMI\<9,2 kg/m2 female: SMI\<7,4 kg/m2

Time frame: Baseline and Month 1

Change from Baseline on Katz Activities of Daily Living Scale at month 3

minimum 0, maximum 6, high scores: better

Time frame: Baseline and Month 3

Change from Baseline on Katz Activities of Daily Living Scale at month 1

minimum 0, maximum 6, high scores: better

Time frame: Baseline and Month 1

Change from Baseline on Short Physical Performance Battery at month 3

0-low perfomance, 12-good performance

Time frame: Baseline and Month 3

Change from Baseline on Short Physical Performance Battery at month 1

0-low perfomance, 12-good performance

Time frame: Baseline and Month 1

Change from Baseline on Berg Balance Test at month 3

maximum 56 point, a score of \< 45 indicates individuals may be at greater risk of falling.

Time frame: Baseline and Month 3

Change from Baseline on Berg Balance Test at month 1

maximum 56 point, a score of \< 45 indicates individuals may be at greater risk of falling.

Data from ClinicalTrials.gov

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