This study is based on pubertal surveillance of fetal ovarian cysts (KOF). Fetal ovarian cysts (KOF) detected during fetal ultrasound examinations occur during the 3rd trimester of pregnancy and are of unknown cause.
These cysts are functional in the vast majority of cases and are therefore likely to disappear spontaneously, but they may become complicated before regressing. Apart from complication, the natural evolution of these cysts, which are said to be "simple" because they are liquid on ultrasound, is towards regression in the first months of neo-natal life. Surveillance during the 1st year of life showed that simple cysts regressed during the 1st trimester. In the case of complicated cysts, oophorectomy was necessary in 9 cases. In the 1-year follow-up, the ovarian recovery rate was significantly different depending on the appearance of the cyst (p\<0.0001); 60 ovaries out of 89 homolateral to the cyst were follicular, of which 48/49 (98%) were carriers of fluid cysts and 12/40 (30%) were initially heterogeneous. The origin of these cysts is unknown, the ovary is again physiologically stimulated during the onset of puberty. No series in the literature gives the long-term ovarian prognosis for these patients. We wish to evaluate the pubertal evolutionary profile of patients followed at the University Hospital for KOF. The data collected concerning puberty (age of menses) will be examined in relation to the age of menses in the siblings and in the mother, as well as to the data in the literature on the age of the first menses in France.
Study Type
OBSERVATIONAL
Enrollment
83
Pubertal course questionnaire
Toulouse University Hospital
Toulouse, France
RECRUITINGAge of onset of first menstruation
Age of onset of first menstruation defined with one decimal place (year and month).
Time frame: Day 1
Average age of maternal and sister rules
Average age of maternal and sister menstruation.
Time frame: Day 1
Ovarian volumes
Homo and contralateral ovarian volumes at the cyst.
Time frame: Day 1
Presence or not of follicles
Presence or not of follicles on both ovaries.
Time frame: Day 1
first menstruation description - age of breast onset
Age of breast onset
Time frame: Day 1
first menstruation description - cycle length
cycle length in the last three months
Time frame: Day 1
first menstruation description - cycle disorder
rate of patients with cycle disorder
Time frame: Day 1
first menstruation description dysmenorrhoea.
dysmenorrhoea.
Time frame: Day 1
first menstruation description menorrhagia
menorrhagia
Time frame: Day 1
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percentage of hyperandrogenism
Percentage of girls with clinical signs of hyperandrogenism or elevated testosterone levels.
Time frame: Day 1
Hormonal levels - AMH
AMH levels
Time frame: Day 1
Hormonal levels - LH
Luteinizing hormone (LH) levels
Time frame: Day 1
Hormonal levels - FSH
follicle stimulating hormone (FSH) levels
Time frame: Day 1
Hormonal levels - estradiol
estradiol levels
Time frame: Day 1
rate of ovarian cyst recurrence
Ovarian cyst recurrence rate
Time frame: Day 1