Infections and Colonization With the Third Group of Enterobacteriaceae in the Intensive Care Unit

Central Hospital, Nancy, France179 enrolled

Overview

There is a lack of data whether colonization and infection with Enterobacteriaceae of the third group (EB3) affect the outcomes for ICU patients. This study evaluated the effects of EB3 colonization and infection on ICU mortality, ICU length of stay (LOS) and broad-spectrum antibiotic exposure. We focused on the sub type Enterobacter regarding its a priori higher risk of resistance.

Study Type

OBSERVATIONAL

Enrollment

179

Conditions

Critically Ill Enterobacteriaceae Infections Antibiotic Resistant Infection

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * adults critically ill patients admitted to the the participating ICUs during the study period * with colonization and/or infection with a third group enterobacteriacea * and with a lenght of stay \> 24h Exclusion Criteria: * minors patients * lenght of stay \< 24h

Locations (1)

Emmanuel NOVY

Vandœuvre-lès-Nancy, Lorraine, France

Outcomes

Primary Outcomes

all cause mortality

Evaluation of the impact of colonization and/or infection with third group enterobacteriaceae on mortality during hospitalization and up to 180 day

Time frame: Day 180

Secondary Outcomes

Resistance strains of sub type enterobacter

Evaluation of number of resistant strains among Enterobacter subtype in comparison with other third group enterobacteriaceae

Time frame: DAY 90

Data from ClinicalTrials.gov

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