Speech disorders affect more than 90% of patients with Parkinson's disease (PD). Neither of conventional drugs nor surgery can effectively improve speech function. Western speech rehabilitation is effective for speech disorders, but the domestic use of those methods used is limited. Our preliminary results revealed that traditional Chinese Yi jin jing tiger roaring speech rehabilitation is effectively in the treatment of speech disorders in PD, however, high-quality clinical evidence is still scarce. In order to solve this problem, we will conduct a prospective cohort study to explore the effects of Yi Jin Jing tiger roaring speech rehabilitation with real-time feedback technique on speech disorders in PD patients. This study will help to establish a set of Chinese Medicine treatment and objective evaluation methods for PD speech disorders.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
20
A traditional Chinese medicine treatment
A active speech rehabilitation method recommended by the Parkinson's Foundation of America
Functional neurosurgery of Shanghai jiaotong university affiliated Ruijin hospital
Shanghai, Shanghai Municipality, China
Differences in Voice Handicap Index (VHI) between treatment conditions in the on- and off- medication states
The Voice Handicap Index is a self-administered instrument, comprising 30 items on voice-related dysfunction. VHI has a range of 0 (normal voice function) to 120 (severe voice dysfunction).
Time frame: Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks
Differences in voice parameters between treatment conditions in the on- and off- medication states
Voice recording at a sampling rate of 44.1 kHz using 16-bit quantification will be conducted in a sound-treated room using a microphone and a digital voice recorder with a mouth-to-microphone distance of 15 cm. The recorded voices will then be used for a composit acoustic analysis.
Time frame: Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks
Differences in Swallowing Disturbance Questionnaire (SDQ) scores between treatment conditions in the on- and off- medication states.
Differences in Swallowing Disturbance Questionnaire (SDQ) scores between treatment conditions in the on- and off- medication states.
Time frame: Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks
Differences in Burg Balance Scale (BBS) scores between two treatment conditions in the on- and off- medication states.
Burg Balance Scale measures patients' static and dynamic balance abilities. BBS score has a range of 0 (severe balance problems) to 56 (no balance problems).
Time frame: Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks
Differences in Water Swallow Test (WST) scores between treatment conditions in the on- and off- medication states.
The Water Swallow Test is frequently used in clinical practice as a functional assessment to detect dysphagia, with stage 1 indicating severe dysphagia and stage 6 indicating normal swallowing function.
Time frame: Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks
Differences in Beck Depression Inventory (BDI) scores between Treatment conditions.
Beck Depression Inventory is a self-administered Instrument, contains 21 self-report items. The items are scored as 0, 1, 2, or 3. The score range is 0 (no depression) to 63 (severe depression).
Time frame: Baseline, 4 weeks
Differences in Beck Anxiety Inventory (BAI) scores between treatment conditions.
The BAI is a rating scale used to evaluate the severity of anxiety symptoms. It contains 21 self-report items. The items are scored as 0, 1, 2, or 3. The score range is 0-63. A total score of 0-7 is considered minimal range, 8-15 is mild, 16-25 is moderate, and 26-63 is severe.
Time frame: Baseline, 4 weeks
Differences in 8-item Parkinson's Disease Questionnaire (PDQ-8) scores between treatment conditions.
8-item Parkinson's Disease Questionnaire is a 8-item health-related quality of life instrument for subjects with Parkinson's Disease, which has a score range of 0 (good life quality) to 32 (very bad life quality).
Time frame: Baseline, 4 weeks
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