This study will evaluate exposure to tar and nicotine from two cigarette products that contain a menthol capsule in the filter, and provide a basis for comparing mouth-level exposure when smokers smoke the two cigarette products.
Subjects will be randomly assigned to the order in which they will smoke two study cigarette products (including one comparator product and one test product). Subjects will smoke each study product exclusively for approximately one week prior to a test visit, with a different product smoked each week over a two-week period. Cigarette butts will be collected the day prior to each test visit for determination of Yield-in-Use (YIU) tar and nicotine levels. Blood samples will be collected at each test visit for determination of blood cotinine levels. Subjects will provide responses to questions during each test visit to assess their cigarette smoking and cigarette butt collection behavior during the preceding day.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
55
High Point Clinical Trials Center
High Point, North Carolina, United States
Yield-in-use tar per cigarette
To compare the per cigarette YIU tar per cigarette from smoking product 1601A with those from smoking product 1601B.
Time frame: 2 weeks
Yield-in-use nicotine per cigarette
To compare the per cigarette YIU nicotine per cigarette from smoking product 1601A with those from smoking product 1601B.
Time frame: 2 weeks
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