The superior vena cava (SVC) is one of the most common non pulmonary vein (PV)-triggers for atrial tachyarrhythmias. SVC electrical isolation can be reached by circular radiofrequency (RF)-ablation under close monitoring of the phrenic nerve. However, adding substrate modification and vein of Marshal (VoM) ethanol infusion to the ablation procedure might substantially improve long-term outcomes. The aim of this study is to evaluate the recurrence rate 1 year after the index ablation in patients undergoing a redo ablation for recurrent paroxysmal atrial fibrillation (PAF) despite durable pulmonary vein isolation (PVI) with either SVC isolation alone or with substrate modification including vein of Marshal ethanolisation in addition to SVC isolation alone
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Patients allocated to this arm will receive an RF ablation with the isolation of the SVC alone
Patients allocated to this arm will receive an RF ablation with the isolation of the SVC, substrate modification and vein of Marshal ethanol infusion
AZ Sint-Jan Brugge-Oostende AV
Bruges, Please Select, Belgium
RECRUITINGRecurrence of atrial tachyarrhythmia 1 year after the index ablation
Comparison of the prevalence of atrial tachyarrhythmia recurrence 1 year after the index ablation between groups
Time frame: 1 year
Safety (complications)
Comparison of the number of procedural complications between groups
Time frame: During procedure
Total procedural time
Comparison of the procedural time between groups
Time frame: During procedure
Fluoroscopy time
Comparison of the fluoroscopy time between groups
Time frame: During procedure
RF ablation time
Comparison of the radiofrequency time between groups
Time frame: During procedure
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