Improving Outcome of Very Preterm Infants Using Collaborative Quality Improvement

Children's Hospital of Fudan University

Overview

A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants in six neonatal centers in Shanghai

A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants using evidence-based collaborative quality improvement interventions including benchmarking, potential better practice list, PDSA implementation and collaborative learning.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Conditions

Morbidity;Newborn Morality

Interventions

Evidence-based collaborative quality improvementBEHAVIORAL

Evidence-based collaborative quality improvement interventions including benchmarking, potential better practice list, PDSA implementation and collaborative learning

Eligibility

Sex: ALLMax age: 120 Days

Medical Language ↔ Plain English

Inclusion Criteria: 1. Infants born at \>=24+0 weeks' gestation and \<32+0 weeks' gestation; 2. Admitted to the participating NICUs within 7 days after birth during study period Exclusion Criteria: 1. Infants with major congenital anomalies; 2. Infants who transferred to non-participating hospitals within 24 hours after birth;

Locations (6)

Obstetrics and Gynecoloy Hospital of Fudan University

Shanghai, Shanghai Municipality, China

Children's Hospital of Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China

Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China

Shanghai First Maternity and Infant Hosipital

Outcomes

Primary Outcomes

Mortality or any major morbidity

It is a binary varibale (1/0). The variabel would be setted into "1",if death or with any of the following major morbidities: bronchopulmonary dysplasia, necrotizing stage II or above, retinopathy of prematurity stage III or above, intraventricular hemorrhage grade III or above or cystic periventricular leukomalacia and late-onset epsis

Time frame: During first NICU hospitalization (about 1-4 months)

Secondary Outcomes

Mortality

It is a binary varibale (1/0). The variabel would be setted into "1",if patients dead during hospitalization or 28 days after discharge against medical advice

Time frame: During the procedure (about 1-4 months)

Bronchopulmonary dysplasia

It is a binary varibale (1/0). The variabel would be setted into "1",if patients reveived respiratory support or oxygen at 36 weeks' corrected gestational age or on discharge

Time frame: During first NICU hospitalization (about 1-4 months)

Necrotizing enterocolitis

It is a binary varibale (1/0). The variabel would be setted into "1",if patients appeared with NEC stage II or above

Time frame: During first NICU hospitalization (about 1-4 months)

Severe brain injury

It is a binary varibale (1/0). The variabel would be setted into "1",if patients appeared with intraventricular hemorrhage grade III or above within 28 days after birth or cystic periventricular leukomalacia

Time frame: During first NICU hospitalization (about 1-4 months)

Retinopathy of prematurity

It is a binary varibale (1/0). The variabel would be setted into "1",if patients appeared with ROP stage III or above.

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.