Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses

Key Inclusion Criteria: * Sign an approved Informed Consent Form. * Wear spherical contact lenses in both eyes for a minimum of 5 days per week and 10 hours per day during the past 3 months. * Willing to wear habitual spectacles for vision correction when study lenses are not worn, as needed. * Other protocol-defined inclusion criteria may apply. Key Exclusion Criteria: * Any eye condition or use of medication that contraindicates contact lens wear, as determined by the Investigator. * History of refractive surgery or plan to have refractive surgery during the study. * Current or history of dry eye in either eye that, in the opinion of the Investigator, would preclude contact lens wear. * Routinely sleeps in contact lenses at least 1 night per week. * Part A: Current wearer of ACUVUE OASYS® with HYDRACLEAR® PLUS. * Part B: Current wearer of Biofinity family of contact lenses (comfilcon A). * Other protocol-defined exclusion criteria may apply.