Effects of Renal Replacement Therapy With Hemoadsoption in Patients With Sepsis

Institutul Clinic Fundeni30 enrolled

Overview

Hemoadsorption has been demonstrated to improve clinical and paraclinical results in critically ill patients with sepsis and septic shock. The present study investigates the effects of three consecutive sessions of hemoadsorption, performed in accordance to the local protocol for treating patients with sepsis, on organ failure, severity scores and 30-days mortality. Paraclinical results and severity scores were obtained before and after the three consecutive sessions.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sepsis

Interventions

CytoSorbPROCEDURE

three consecutive sessions of hemoadsorption in patients with sepsis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients with sepsis or septic shock who require hemoadsorption in accordance with local guidelines Exclusion Criteria: * unsigned informed consent * duration of therapy under 12 hours * death before the three consecutive sessions

Locations (1)

Fundeni Clinical Institute

Bucharest, Romania

Outcomes

Primary Outcomes

28-days mortality

Time frame: 28 days after ICU admission

Secondary Outcomes

severity score

dynamics of SOFA score (Sequential Organ Failure Assessment) calculated as the mathematical difference in post-therapy SOFA score and pre-therapy SOFA score

Time frame: 3 days

Data from ClinicalTrials.gov

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