A multicenter prospective cohort study performed at 6 major teaching hospitals in Southern Norway to study patient reported outcomes, lung function and pulmonary CT in patients at 3 and 12 months after hospitalization for coronavirus disease 2019 (COVID-19).
This cohort study aim to describe the Natural course of COVID-19 disease in an consecutive and unselected cohort of Norwegians that have been hospitalized. In addition to the primary and secondary outcomes related to PROMS, lung function and pulmonary CT, the study also have several substudies: Cardiology: The study includes echocardiography, 24-h electrocardiography and cardiopulmonary exercise test. ENT: The study includes CT of head sinuses and patient-reported sleep disturbances and nose symptoms in a subgroup of patients. Laboratory: Analyses of common markers of inflammation and cardiac biomarkers.
Study Type
OBSERVATIONAL
Enrollment
264
No interventions
Dept Pulmonary Medicine
Lørenskog, Akershus, Norway
Forced vital capacity
L
Time frame: 3 months
Forced vital capacity
L
Time frame: 12 months
Gas diffusion capacity of carbon monoxide
mmol/kPa\*min
Time frame: 3 months
Gas diffusion capacity of carbon monoxide
mmol/kPa\*min
Time frame: 12 months
modified Medical Respiratory Council Dyspnea Scale
Unit
Time frame: 6 weeks
modified Medical Respiratory Council Dyspnea Scale
Unit
Time frame: 3 months
modified Medical Respiratory Council Dyspnea Scale
Unit
Time frame: 12 months
Parenchymal opacities of the lungs
Number of opacities in one lung zone
Time frame: 3 months
Parenchymal opacities of the lungs
Number of opacities in one lung zone
Time frame: 12 months
Forced expiratory capacity during 1st second of expiration
L
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Time frame: 3 months
Forced expiratory capacity during 1st second of expiration
L
Time frame: 12 months
FEV1/FVC
Percentage
Time frame: 3 months
FEV1/FVC
Percentage
Time frame: 12 months
Gas diffusion capacity adjusted for alveolar ventilation (KCO)
mmol/kPa\*min\*L
Time frame: 3 months
Gas diffusion capacity adjusted for alveolar ventilation (KCO)
mmol/kPa\*min\*L
Time frame: 12 months