Hormonal Status and Quality of Life in Female Postmenopausal Patients With Burning Mouth Syndrome

University of Zagreb40 enrolled

Overview

The aim of this study was to determine the level of salivary estradiol, progesterone and dehydroepiandrosterone in female postmenopausal women with and without burning mouth syndrome. In all participants the quantity of unstimulated and stimulated saliva would be determined and they would fulfill self-perceived quality of life questionnaire Oral Health Impact Profile-14 (OHIP-14). Intensity of burning symptoms would be determined on visual-analogue scale grading 0-10. All data would be compared between study and control group.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Burning Mouth Syndrome Progesterone Dehydroepiandrosterone Quality of Life Hormone Disturbance 17β-Estradiol

Interventions

Eligibility

Sex: FEMALEMin age: 51 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * postmenopausal women with burning mouth syndrome Exclusion Criteria: * women with burning mouth syndrome who are not in menopause

Outcomes

Primary Outcomes

to evaluate the levels of salivary hormone

levels of salivary 17β-Estradiol, progesterone and DHEA were determined in study and control group

Time frame: November 2019-June 2020

Secondary Outcomes

to evaluate quality of life and correlate it with levels of salivary hormones and intensity of symptoms

quality of life was evaluated with self-perceived questionnaire OHIP-14