Impact of CKD on Children and Their Families

Cairo University100 enrolled

Overview

Based on the available literatures, previous studies have investigated the impact of CKD and dialysis on patient's health among adult and elderly population. As far as we know, this is the first empirical study that investigates the impact of CKD on children functional capacity and their families QOL.

The current study will be done to investigate the long term effect of the CKD itself on different dimensions of the child health to understand the unique characteristics of pediatric CKD. Also, it will be beneficial for designing a comprehensive physical therapy protocol for prevention of different complications and to improve their wellbeing healthcare. Additionally, it will be beneficial to determine the family and parental stresses and to build the rehabilitation plan for the child considering the possible family issues regarding the child condition.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

CKD (Chronic Kidney Disease) Stage 5D

Interventions

functional capacityOTHER

impact of hemodialysis on functional capacity in children with CKD

muscle strengthOTHER

impact of hemodialysis on muscle strength in children with CKD

Quality of life of childrenOTHER

impact of hemodialysis on Quality of life in children with CKD

Eligibility

Sex: ALLMin age: 8 YearsMax age: 12 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age from eight to twelve years. * Both genders. * Diagnosed with ESRD (stage 5) based on the glomerular filtration rate (GFR \< 15 mL/minute/1.73 m2). * Able to understand and follow instructions during assessment procedures. * Willing to participate in the study and attend the assessment procedures. Exclusion Criteria: Children of the following criteria will be excluded from the study: * Cardiopulmonary disorders * Uncontrolled hypertension * Unstable angina * Severe uncontrolled diabetes * Neurological or cognitive disorders with functional deficits * Significant cerebral or peripheral vascular disease.

Outcomes

Primary Outcomes

functional capacity

6 minute walking test is commonly used to evaluate functional capacity in children with CKD. It is a simple, practical, reliable, and valid measure of submaximal exercise capacity in healthy children and children with chronic disease or neuromuscular disorders or cardiopulmonary disease

Time frame: 6 months

Secondary Outcomes

muscle strength

Hand grip strength HGS is a noninvasive and reliable method for assessment of muscle power and nutritional status in CKD children

Time frame: 6 months

quality of life of children

The Arabic version of the PedsQLTM 4.0 Generic Core Scales version proved to be understandable and feasible to use. It showed good reliability for healthy children and children with chronic medical conditions and their parents.

Time frame: 6 months

quality of life of families of children with CKD

The PedsQL FIM appears to be a useful tool for the assessment of family impact on children with ESRD

Time frame: 6 months

Central Contacts

Shaymaa R Mahmoud, Master

CONTACT

01145050053 - 01002452555 shaymaarushdy@gmail.com

Data from ClinicalTrials.gov

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