Mesenteric SParIng Versus Central mesenterectomY in Ileocolic Resection for Terminal Ileitis in Crohn's Disease

Inclusion Criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: 1. Ileocolic disease with an indication for ileocecal resection 2. Concurrent therapies with corticosteroids, 5-ASA drugs, thiopurines, MTX, antibiotics, and anti-TNF therapy are permitted. 3. All patients should have undergone a colonoscopy and MR enterography (or CT enterography if MR contraindicated) in last 3 months to assess extent of disease. 4. Ability to comply with protocol. 5. Competent and able to provide written informed consent. 6. Patient must have been discussed in the local MDT Exclusion Criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: 1. Inability to give informed consent. 2. patients less than 16 years of age. 3. Patients undergoing repeated ileocolic resection. 4. Clinically significant medical conditions within the six months before the operation : e.g. myocardial infarction, active angina, congestive heart failure or other conditions that would, in the opinion of the investigators, compromise the safety of the patient. 5. History of cancer \< 5 years which might influence patients prognosis 6. Emergent operation. 7. Pregnant or breast feeding. 8. Inability to follow up at 3, 6 and 12 months for postoperative assessment, imaging and endoscopy.