Evaluation of Intravenous Infusion of Labetalol Versus Magnesium Sulfate

Inclusion Criteria: * acceptance * 21 to 45 years old. * mass index ≤ 35 kg/m2. * Singleton Pregnant female complicated with severe preeclampsia * Systolic blood pressure ≥ 160 mmHg or diastolic blood pressure ≥ 110 mmHg on two occasions at least 4 hours apart * Thrombocytopenia (platelet count less than 100,000 ) * Impaired liver function indicated by elevated liver enzymes (to twice the upper limit normal concentration), and severe persistent right upper quadrant or epigastric pain not responding to medications and not explained by another diagnosis. * Renal insufficiency (serum creatinine concentration more than 1.1 mg/dL or doubling of the serum creatinine concentration in the absence of other renal disease) * Pulmonary edema * New-onset headache unresponsive to medications and not accounted for by alternative diagnoses * Visual disturbances. Exclusion Criteria: * Preexisting heart disease * Known pulmonary disorders. * Inadequate temporal window. * Atrial fibrillation and any rhythm abnormality. * History of allergy or contraindications to either magnesium sulfate or labetolol. * Exposure to any of the study medications within 24 hours of enrollment.