MolecuLight is a device that utilizes a special light which, when used on wounds, helps identify the regions which pathogenic bacterial counts are the highest. The device applies 405nm violet light which is harmless to the human tissue. When specific components in bacteria catches up the light, a photoluminescent reaction is triggered and the fluorescence light is caught by the camera on this device in real time. When treating an infected wound which requires debridement and/or reconstruction, traditionally surgeons rely on many clinical clues to judge the severity and region of infection. However, these clues, such as lab data, vital signs, bacterial culture growth, or infection symptoms/signs, are usually indirect and also require several days to be fully interpretated. The advantage of MolecuLight is its simple, direct, real-time, and flexible application, which is very important and valuable when treating an infected wound. We aim to add this device to our routines and see if the treatment course for these wounds can be more rapid and effective, and also utilize the countless potential of immediate bacterial identification in numerous aspects of our work.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
200
MolecuLight is a device that utilizes a special light which, when used on wounds, helps identify the regions which pathogenic bacterial counts are the highest. The device applies 405nm violet light which is harmless to the human tissue. When specific components in bacteria catches up the light, a photoluminescent reaction is triggered and the fluorescence light is caught by the camera on this device in real time.
Shuang Ho Hospital First Medical Building
New Taipei City, Taiwan
RECRUITINGPercentage of residual bacterial light spots
The percentage of residual bacterial light spots. After each debridement, we use MolecuLight to evaluate the residual shinny area (post-debridement shinny area/pre-debridement shinny area)
Time frame: Immediately after each debridement within surgery
Numbers of Re-debridement
If the bacterial shinny area after debridement \> 10% wound area, the debridement will be performed again until \< 10% residual bacterial shinny area
Time frame: Immediately after each surgery
Duration of wound healing
Time of complete epithelialization without drainage
Time frame: Time of complete epithelialization without drainage
Incidence of surgical complications
Incidence of wound bleeding, infection and necrosis after debridement
Time frame: 8 weeks postoperatively
Antibiotic use
The amount (regimen and dosage)
Time frame: 8 weeks postoperatively
Duration of antibiotic use
Time frame: 8 weeks postoperatively
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