Post-stroke cognitive impairment is common in stroke survivors. Cognitive function is related to walking ability. The dual task walking is required for daily activities, however, such ability is even more challenging than single walking for people with stroke. The purpose of present study is to investigate the effects of combining cognitive and treadmill training on cognitive function and dual task walking performance in chronic stroke patients with cognitive impairment.
This is a single-blinded, randomized controlled trial with pre- and post-measurements. 24 subjects will be recruited, and randomly assigned to one of two groups: cognitive training during treadmill training group (experimental group) and treadmill training group (control group). The intervention for both group will be 30 minutes per session, 3 sessions per week for a total of 4 weeks. Statistical data analysis will use the SPSS 25.0. Baseline characteristics will be analyzed using independent t-test or Chi-square test. Repeated measures two-way analysis of variance (ANOVA) with Tukey's post-hoc analysis will be used to compare between time and groups. The significant level is set at 0.05.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
8
Treadmill training includes warming up for 3 minutes, training for 25 minutes, and relaxing for 2 minutes. The speed of the treadmill during the warm-up and relaxation period is based on the participant's Borg's rating of perceived exertion (RPE) 7-9 points (very slight to very slight), and the RPE during the training period does not exceed 10\~12 points (slight), and ensures that patients can be cognitively trained at the same time. The cognitive training tasks will be projected on the screen and the participant have to answer the task orders during treadmill training simultaneously.
Treadmill training includes warming up for 3 minutes, training for 25 minutes, and relaxing for 2 minutes. The speed of the treadmill during the warm-up and relaxation period is based on the participant's Borg's rating of perceived exertion (RPE) 7-9 points (very slight to very slight), and the RPE during the training period does not exceed 10\~12 points (slight).
National Yang-Ming University
Taipei, Beitou District, Taiwan
Trail-making test A&B
executive function (s)
Time frame: 8 minutes
Stroop test
attention (number)
Time frame: 10 minutes
Digit span test
memory (number)
Time frame: 8 minutes
Clock drawing test
visuospatial function (score 1-10)
Time frame: 10 minutes
Single walking performance- speed (cm/s)
walking speed in centimeters per second will be calculated during the single walking by using the GaitRite system
Time frame: 3 minutes
Single walking performance-step length (cm)
step length in centimeters will be calculated during the single walking by using the GaitRite system
Time frame: 3 minutes
Single walking performance-step time (s)
step time in seconds will be calculated during the single walking by using the GaitRite system
Time frame: 3 minutes
Single walking performance-cadence (steps/min)
cadence in steps per minute will be calculated during the single walking by using the GaitRite system
Time frame: 3 minutes
Cognitive dual task walking performance-speed (cm/s)
walking speed in centimeters per second will be calculated during the cognitive dual task walking by using the GaitRite system
Time frame: 3 minutes
Cognitive dual task walking performance-step length (cm)
step length in centimeters will be calculated during the cognitive dual task walking by using the GaitRite system
Time frame: 3 minutes
Cognitive dual task walking performance-step time (s)
step time in seconds will be calculated during the cognitive dual task walking by using the GaitRite system
Time frame: 3 minutes
Cognitive dual task walking performance-cadence (steps/min)
cadence in steps per minute will be calculated during the cognitive dual task walking by using the GaitRite system
Time frame: 3 minutes
Cognitive dual task walking performance-dual task cost (%)
dual task cost (%) will be calculated with the following formula: \[(dual-task performance-single task performance) / single task performance\] × 100%
Time frame: 3 minutes
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