FIBRACEP is an onion based fiber that has demonstrated in vitro and in animal models the capacity to increase HDL cholesterol levels as well to improve other lipid profile species. This intervention aims to demonstrate FIBRACEP's blood lipid profile improvement effect. For that purpose, hypercholesterolemic subjects will be recruited and given a daily dose of 7 g of FIBRACEP for two months. Changes in blood lipid profile will be the end-point of the study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
90
A total intake of 7 g/day of FIBRACEP (provided in 6 cookies of 15 g/each) during two months
A total intake of 7 g/day of wheat bran (provided in 6 cookies of 15 g/each) during two months
A total intake of 7 g/day of psyllium plantago (provided in 6 cookies of 15g/each) during two months
José Serrano Casasola
Lleida, Spain
Blood HDL-cholesterol
Cholesterol content in HDL lipoproteins determined by nuclear magnetic resonance
Time frame: 2 months
Blood lipid profile
Cholesterol content in LDL, VLDL (Very low-density lipoproteins) density and IDL lipoproteins determined by NMR
Time frame: 2 months
Blood lipoprotein number
Number of lipoproteins determined by nuclear magnetic resonance
Time frame: 2 months
Blood lipoprotein size
The average size of each lipoprotein specie (HDL, LDL, VLDL, IDL) determined by nuclear magnetic resonance
Time frame: 2 months
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