study of the efficacy and safety of carbon dioxide in cardiac surgery: repeated or minimally invasive
prospective randomized clinical single-center study of the efficacy and safety of using carbon dioxide in deaeration of cardiac cavities during cardiac surgery (repeated interventions and minimally invasive interventions)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
Carbon dioxide insufflation at a rate of 5 l / min. through the Redon drainage during cardiac surgery (minimally invasive or repeated) during cardiopulmonary bypass
standard methods of deaeration of cardiac cavities: manual method, change in body position, through the cannula of the ascending aorta, through the drainage of the left ventricle
"E.Meshalkin National medical research center" of the Ministry of Health of the Russian Federation
Novosibirsk, Russia
RECRUITINGdelirium: CAM-ICU, 3-D CAM
positive test development of postoperative delirium: Richmond Agitation-Sedation Scale, Confusion Assessment Method-Intensive Care Unit (more than one error) - while in the intensive care unit; positive test the 3-Minute Diagnostic Interview for Confusion Assessment Method (CAM) defined delirium - while in the ward of the department: The CAM algorithm is considered positive if the following features are present: Feature 1) Acute onset or fluctuating course and Feature 2) Inattention and either Feature 3) Disorganized thinking or Feature 4) Altered level of consciousness.
Time frame: 7 days after surgery
deaeration time
deaeration time according to transesophageal echocardiography data
Time frame: intraoperatively
neurocognitive dysfunction
development of neurocognitive dysfunction: Montreal Cognitive Assessment - two days before surgery and 7 days after surgery
Time frame: 7 days after surgery
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