prospective study for response of neoadjuvant chemotherapy in metaplastic carcinoma of triple negative breast cancer
Vimentin/Pan CK staining will be performed on tissues of patient who visited Seoul National University Hospital and were diagnosed with triple negative breast cancer and decided to perform neoadjuvant chemotherapy under clinical judgement. Histologically determined to be a metaplastic breast cancer or tested positive for vimentin/Pan CK patients decides as the metaplastic breast cancer. They evaluate the response rate of the neoadjuvant chemotherapy. Patients with vimentin/Pan CK negative are diagnosed with non-metaplastic breast cancer and this group also confirms the response rate of neoadjuvant chemotherapy. The group of metaplastic breast cancer will enroll 50 people, and the group of non-metaplastic breast cancer will enroll 100 people.
Study Type
OBSERVATIONAL
Enrollment
3
Vimentin/pan CK stain positive/negative
Seoul National University Hospital
Seoul, Jongno-gu, South Korea
response rate of neoadjuvant chemotherapy
response criteria for neoadjuvant chemotherapy-complete response (CR), partial response (PR), and no response (NR)
Time frame: After neoadjuvant chemotherapy was finished. Average 6 month later.
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