Mannose Binding Lectin Gene Polymorphism Versus Microbial Virulence in the Pathogenesis of Vulvovaginal Candidiasis

Aljazeera Hospital50 enrolled

Overview

The vaginal mucosa is inhabited by both fungal and bacterial microorganisms which normally co-exist with the host in a tightly regulated and commensal manner.

Nevertheless, under certain circumstances, this co-existence can turn into a pathologic state followed by symptomatic disease

Study Type

OBSERVATIONAL

Enrollment

Conditions

Infection

Interventions

blood sampleDIAGNOSTIC_TEST

Whole blood was collected on EDTA (1mg/ml) to prevent clotting and DNA degradation.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 42 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 1\. Married females in the reproductive age period. 2. Females complaining of vaginal discharge (whitish and scanty), itching, dyspareunia, pruritis, and signs of vulvovaginitis ie. erythema. Exclusion Criteria: * females who attended the same clinic in the same period, matched the cases regarding the age group, without having Candida infection as confirmed by culture of vaginal swabs.

Locations (1)

Algazeerah

Giza, Egypt

RECRUITING

Outcomes

Primary Outcomes

the number of women who have mutation in MBL2 gene polymorphism

women who have mutation in MBL2 gene polymorphism

Time frame: a month

Central Contacts

Mahmoud Alalfy

CONTACT

01002611058 mahmoudalalfy@ymail.com

Ahmed Elgazzar

CONTACT

01014005959 elgazzara50@gmail.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.