Use of Jet-injection in Photodynamic Therapy for Basal Cell Carcinoma

Inclusion Criteria: Subjects who meet all of the following criteria are eligible to participate in this study * Histologically-verified, previously untreated low-risk mixed superficial and nodular BCC(s) or nodular BCC(s) \< 1 cm in diameter on scalp, extremities, or trunk. * ≥ 18 years of age * Owner of a smartphone (Android or iPhone). Patients without a working smartphone will not be considered eligible for this study. * Being able to download application on their phone * Being able to take pictures of their treated BCC(s) (with or without assistance) * Female subjects of childbearing potential must be confirmed not pregnant by a negative urine pregnancy test prior to trial treatment. (Female subjects are considered of childbearing potential unless they have been hysterectomized or have undergone tubal ligation or have been post-menopausal for at least one year prior to the first visit) * Legally competent, able to give verbal and written informed consent * Subject in good general health and willing to participate comply with protocol requirements. * Superficial and nodular BCC(s) Exclusion Criteria: Subjects meeting any one of the following criteria are not eligible to participate in this study * High-risk BCC(s) (H area, \>1 cm in M area, or \>2 cm in L area) * BCC(s) subtype morpheaform * Diagnosed with gorlin syndrome * Receiving immunosuppressive medication * Subjects with a known allergy to ALA * Individuals with other interfering skin diseases in the area of treatment * Subjects with a tattoo in the treatment area which may interfere with or confound the evaluation of the study * Subjects with a history of keloids which is deemed clinically relevant in the opinion of the investigator * Lactating or pregnant women * Patient who are taking prescription pain medications or can not stop OTC pain medications.