The Hybrid Combination of CCTA and SPECT and CAG for Evaluation Prognosis of CAD: an Observational Follow-up Study

The First Affiliated Hospital with Nanjing Medical University550 enrolled

Overview

A total of 550 patients with stable angina (40-70% stenosis) tested by coronary CT angiography (CCTA) and single photon emission computed tomography (SPECT) and coronary angiography (CAG) within 3 months were retrospectively recruited from 2005 to 2015 and follow up to 5 years. A new hybrid software was used to analysis the image data.

Study Type

OBSERVATIONAL

Enrollment

550

Conditions

Coronary Disease

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age: 18-70 2. Gender: All 3. coronary artery disease patients (CAD) 4. underwent CCTA, SPECT and coronary angiography (CAG) together within 3 months 5. Time: 2005-2015 Exclusion Criteria: 1. dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), congenital heart disease (CHD), atrial fibrillation (AF), ventricular tachycardia (VT) 2. Prior coronary revascularization; 3. permanent pacemaker or internal defibrillator 4. prosthetic heart valve 5. coronary image lose 6. coronary artery severe calcification 7. motion artifacts and poor CCTA image quality

Outcomes

Primary Outcomes

Major adverse cardiac events (MACE)

All-cause death, cardiac death, ischemic stroke, unplanned revascularization and nonfatal myocardial infarction

Time frame: 5 YEARS

Data from ClinicalTrials.gov

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