Hemodynamic Impact on Critical Care Patients With Lung Damage Secondary to COVID-19

Juan Victor Lorente67 enrolled

Overview

The aim of the present work is to describe the hemodynamic effects shown in patients with ARDS secondary to SARS-CoV-2 infection

Study Type

OBSERVATIONAL

Enrollment

Conditions

Covid19 Hemodynamic Instability ARDS, Human

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients over 18 years old. * Patients that are classified as a "confirmed case" according to criteria established by the Spanish Ministry of Health in its Technical Document updated on March 31, 2020. This defines a "confirmed case" as a case that meets laboratory criteria (Positive PCR test for any of the SARS-CoV-2 genes). * Patients admitted to ICU. * Presence of Kirby index (PaFi) less than or equal to 300 mm Hg, with PEEP or CPAP greater than or equal to 5 cmH2O. * Need for radial artery cannulation for hemodynamic monitoring and/or repeated monitoring of blood gases at the discretion of the responsible physician. * Patients who agree (or a representative of the patient if sedated) to participate in study and who provide written informed consent. Exclusion Criteria: * Patients being treated with veno-venous or veno-arterial ECMO * Patient with therapeutic restrictions due to life support * Patient who presents a complication that requires surgical intervention.

Locations (5)

1. A.H. Juan Ramón Jiménez.

Huelva, Andalusia, Spain

5. Hospital Virgen de la Victoria

Málaga, Andalusia, Spain

4. Hospital Universitario de Álava.

Alava, Basque Country, Spain

3. Hospital Universitario. Jerez de la Frontera.

Jerez de la Frontera, Cádiz, Spain

Outcomes

Primary Outcomes

Total amount of hypotension

Hypotension will be defined as a hemodynamic event that occurs when the MAP falls below 65 mmHg for a minimum duration of 1 minute (3 consecutive recordings of 1 minute or more between two consecutive falls of the MAP).

Time frame: 5 days

Secondary Outcomes

Minimally invasive hemodynamic monitoring and related variables obteined from HemoSphere platform with Acumen IQ sensor (Stroke volume)