Major Complication Rate in Cancer Patients With Neutropenic Fever Potentially Eligible for a Hospital at Home Program

M.D. Anderson Cancer Center

Overview

This study investigates the major complication rate in cancer patients potentially eligible for a hospital at home program for management of neutropenic fever. "Hospital at Home" is a home care program that provides acute, inpatient care in a patient's home in place of a traditional hospital stay. Learning more about the characteristics of potentially eligible patients, including reasons for inpatient admission, rates of major complications, and situations or treatments that would be difficult to deliver in an at home setting may help to inform future program development.

PRIMARY OBJECTIVE: I. Estimate the major complication rate among patients potentially eligible for a hospital at home program for management of neutropenic fever. SECONDARY OBJECTIVES: I. Describe the demographic and clinical characteristics of patients potentially eligible for admission to a hospital at home program for management of neutropenic fever. II. Describe situations or treatments experienced by potentially eligible patients admitted for neutropenic fever that would be difficult to accomplish in a hypothetical hospital at home program (e.g., blood transfusions, echocardiograms, computed tomography \[CT\] scans). OUTLINE: Patients' medical charts are reviewed.

Study Type

OBSERVATIONAL

Conditions

Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm

Interventions

Medical Chart ReviewOTHER

Review of medical charts

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Admitted to MD Anderson Cancer Center through the Emergency Center with a diagnosis of neutropenic fever between 1/1/2019 and 12/31/2019 * Be at low risk for major complications as defined by a Multinational Association for Supportive Care in Cancer (MASCC) score \< 21 Exclusion Criteria: * Reside in a nursing home * Homelessness * Hospice enrollment * A secondary reason for admission to the hospital or high risk clinical feature not captured in the MASCC score that places them at high risk for major complications in a hospital at home program

Outcomes

Primary Outcomes

Percentage of patients who experience major complications that require escalated care

Percentages will be presented with exact binomial 95% confidence interval. Also, will identify significant predictors of major complications (yes or no) using univariable logistic regression.

Time frame: 1 month

Secondary Outcomes

Patient demographic, clinical, and psychosocial features

Will describe the study sample demographic, clinical, and psychosocial features. Descriptors will include frequencies, percentages, means with standard deviations, or medians with interquartile ranges, and minimum and maximum values as appropriate.

Time frame: 1 month

Situations or treatments experienced by potentially eligible patients admitted for neutropenic fever that would be difficult to accomplish in a hypothetical hospital at home (HaH) program

Will enumerate situations and treatments observed in the study sample that could not be handled optimally in the HaH environment.

Time frame: 1 month

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.