PREDICT is an observational study following adults with an unprovoked seizure or epilepsy in the health care region of western Sweden. The objective is to identify biomarkers and/or genetic predisposition of relevance for diagnosis and/or treatment of epilepsy and study the long-term prognosis and consequences of epilepsy.
Adults over 18 years of age, with an unprovoked seizure in the last year or epilepsy, resident in the health care region of western Sweden (VGR) at the time of inclusion. Baseline data and outcome variables are collected from several patient registries: the electronic medical records system in the health care region VGR and Swedish National Registers of healthcare, income, and employment managed by The National Board of Health and Welfare or Statistics Sweden, both of which are government agencies.
Study Type
OBSERVATIONAL
Enrollment
1,000
We will collect information on first seizure ever, last seizure ever, number of seizure in last two months.
We will collect results from imaging, electroencephalogram, and laboratory tests.
We will collect information on risk factors of epilepsy, cause of epilepsy, epilepsy type/syndrome, medications tried, if the epilepsy is drug resistent, side effects of antiepileptic drugs.
Södra Älvsborgs Sjukhus
Borås, Sweden
RECRUITINGSahlgrenska University Hospital
Gothenburg, Sweden
RECRUITINGSjukhusen i Väster
Gothenburg, Sweden
RECRUITINGepilepsy
more than one seizure after first seizure
Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10
seizure status
the number of seizures in last two months and overall
Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10
drug resistant epilepsy
epilepsy that has not responded to two antiepileptic drugs
Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10
severe side effects of antiepileptic drug
Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10
psychosocial outcomes
employment, marital status, income, sick leave
Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10
received health care
the number of visits for epilepsy, missed appointments, time intervals between visits
Time frame: baseline and years 1,2,3,4,5,6,7,8,9,10
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We will collect information on age, sex, date of death if applicable, marital status, education level, income type, driving status, employment, benefits, sick leave, number of household members.
We will collect information on received health care; visit dates, caregiver, dispensation dates of antiepileptic drugs