Protective Effect of Intraoperative Parathyroid Gland Auxiliary Recognition System in Thyroid Malignant Tumor Operation

Fudan University200 enrolled

Overview

This intraoperative parathyroid gland auxiliary recognition system uses the principle of parathyroid gland autofluorescence to assist surgeons in accurately identifying and protecting parathyroid glands during surgery, reducing the possibility of postoperative hypoparathyroidism. This study will explore the protective effect of the parathyroid gland auxiliary recognition instrument on parathyroid function during thyroid malignant tumor surgery through reasonable grouping.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

200

Conditions

Parathyroid Intraoperative Monitoring Thyroid Cancer

Interventions

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with unilateral thyroid malignancies who require surgical treatment between the ages of 20-50. 2. No history of neck surgery and radiotherapy. 3. There is no evidence of parathyroid tumor invasion in preoperative imaging assessment. 4. No abnormal calcium metabolism disease. 5. No abnormalities in blood calcium and blood PTH before operation. 6. No allergy to contrast agents. 7. The patient or his agent signs an informed consent statement. Exclusion Criteria: 1. Does not meet the entry criteria; 2. Parathyroid glands were found to be invaded by tumor during operation and the parathyroid glands could not be preserved.

Outcomes

Primary Outcomes

Serum Calcium level

Patients' serum Calcium level at 24 hours after surgery.

Time frame: 24 hours after surgery

Serum Calcium level

Patients' serum Calcium level at 1 month after surgery.

Time frame: 1 month after surgery

PTH

Patients' serum PTH level at 24 hours after surgery.