to determine safety and efficacy of Tranexamic Acid in reducing blood loss during Myomectomy in our institution.
A double blinded randomized controlled trial in which cases were given 1000mg intravenous tranexamic acid into 1L of intravenous normal saline and control were given 10mls of placebo water for injection into same amount of intravenous fluid. outcome of both groups in terms of intraoperative blood loss, duration of surgery, postoperative packed cell volume and total blood loss with risk of blood transfusion were then determined.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
59
intravenous perioperative tranexamic acid was added into infusion of normal saline for the cases while placebo of intravenous water for injection was added into normal saline perioperatively for control
AEFUTHA
Abakaliki, Ebonyi State, Nigeria
Average duration of surgery in each group
Average duration of Surgeries were calculated for each group
Time frame: one year
Mean intraoperative Blood loss
The mean intraoperative blood loss was calculated for both groups
Time frame: one year
Postoperative Haemoglobin concentration
Average Postoperative Haemoglobin concentration of both groups were determined
Time frame: one year
Blood Transfusion
Risk of Blood Transfusion of both groups were determined
Time frame: One year
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