This study aims to determine how long COVID-19 neutralizing antibodies can be detected in an elderly institutionalized population presenting fragility factors. This study also aims to stratify seroconversion by immunological profiles of the elderly patients residing in the EHPAD. This stratification requires the measurement of immunological marker levels already described in immunosenescence and also involved in the development of certain chronic infectious diseases more common in the elderly population. This analysis will enable the investigators to describe an immunological, clinical and biological profile representing a patient who has developed an immunity against COVID 19. It will also help the investigators to understand the different mechanisms leading to a reduced immune response after a potential administration of a vaccine. Finally, it will help describe the immune profiles of elderly residents who presented with non-severe forms of COVID-19.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SCREENING
Masking
NONE
Enrollment
98
Sample collection of 4 to 10 tubes of whole blood will be done according to centre Saint-Victor's protocol.
CHU Amiens
Amiens, France
titers of COVID-19 neutralising antibodies
Time frame: day 0
titers of COVID-19 neutralising antibodies
Time frame: at 3 months
titers of COVID-19 neutralising antibodies
Time frame: at 6 months
titers of COVID-19 neutralising antibodies
Time frame: at 9 months
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