Feasibility - Infinitome

HealthPartners Institute4 enrolled

Overview

The Infinitome Program from Omniscient has the ability to identify abnormal brain networks or connectomes using resting state functional MRI (rs-fMRI). This technology, which visualizes brain networks in three dimensions, was originally developed to ensure neurosurgeons avoid inadvertently lesioning cognitively eloquent brain regions during surgical operations. The potential of Infinitome in identifying connectome dysfunction for neurodegenerative diseases such as Alzheimer's disease has yet to be explored. This diagnostic technique may play a critical role for identifying disease brain networks that may benefit from targeted interventions in clinical trials.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Alzheimer Disease

Interventions

InfinitomePROCEDURE

Added sequence of rs-fMRI.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with a diagnosis of mild, moderate, or severe Alzheimer's disease 2. Age: 40 - 90 Years 3. Patients who are clinically indicated for an MRI Exclusion Criteria: 1. fMRI contraindicated (eg. Implantable device, pacemaker, metallic implants, etc.) 2. Subject unable to tolerate sitting for a one hour fMRI 3. Other concerns as determined by the investigator

Locations (1)

HealthPartners Neuroscience Center

Saint Paul, Minnesota, United States

Outcomes

Primary Outcomes

Number of Participants Who Completed Rs-fMRI

Percent of subjects who complete the sequence of the fMRI protocol. Range: 0-100. Higher percentage indicates more completion.

Time frame: 4 months

Number of Subjects Whose Images Completed Analysis

Percent of subjects whose images were uploaded and analyzed by the Infinitome program. Range: 0-100. Higher percentage indicates more completion.

Time frame: 4 months

Data from ClinicalTrials.gov

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