Observational Registry to Evaluate Real World Usage of PiCSO Impulse System in STEMI Patients as Part of Post-marketing Surveillance

Inclusion Criteria: 1. Age ≥18 years old 2. Culprit lesion in proximal or mid LAD 3. ST-segment elevation 4. Pre-PCI TIMI flow 0 or 1. 5. Symptoms onset time consistent with myocardial ischemia (e.g. persistent chest pain, shortness of breath, nausea/vomiting, fatigue, palpitations or syncope) ≤ 12 h. 6. Patient is deemed eligible for PCI 7. Consent as per approved national ethical committee specific requirements prior to the procedure. Exclusion Criteria: 1. Patients with contraindications to percutaneous insertion or angiography 2. Patients with implants or foreign bodies in the coronary sinus 3. Known allergy to polyurethanes, PET or stainless steel 4. Known pregnancy or breast feeding 5. Known pericardial effusion or cardiac tamponade 6. Known central hemodynamically relevant left/right shunt 7. Patients with symptom onset \> 12 hours 8. Patients with previous CABG 9. Patients with a history of stroke, TIA or reversible ischemic neurological deficit within last 6 month. 10. Patients with coagulopathy 11. Patients under judicial protection, legal guardianship or curatorship.