Specific Methylation Profiles in HNSCC

Aalborg University Hospital300 enrolled

Overview

In the study, N-20190047, the investigators aim to define specific methylation patterns in a group of patients with head and neck squamous cell carcinomas. With this study the investigators aim to validate these findings in a larger cohort.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

Blood sampleDIAGNOSTIC_TEST

A separate blood sample will be taken for methylation-analyses

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Cancer group: Inclusion Criteria: * Written informed consent * Verified head and neck squamous cell carcinoma Exclusion Criteria: * Other active cancer * Uncontrolled comorbidity * Unable to give informed consent Control group: Inclusion Criteria: * Written informed consent * Normal ENT-examination Exclusion Criteria: * Other active cancer * Uncontrolled comorbidity * Unable to give informed consent

Locations (1)

Department of Otolaryngology - Head and Neck Surgery

Aalborg, Denmark

RECRUITING

Outcomes

Primary Outcomes

Diagnostic accuracy

How accurate can the methylation profiles diagnose the head and neck squamous cell carcinoma

Time frame: At diagnosis

Central Contacts

Christian Danstrup, M.D.

CONTACT

+45 23800598 csd@rn.dk

Michael Gaihede, Professor

CONTACT

Data from ClinicalTrials.gov

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