Automated Retinal Image Analysis System (EyeQuant) for Computation of Vascular Biomarkers

Mayo Clinic80 enrolled

Overview

This study aims to provide clinical validation of EyeQuant, a fully automated retinal image analysis system for computation of vascular biomarkers indicative of cognitive disorders, using retinal fundus photographs collected from patients with mild cognitive impairment, Alzheimer's disease, and vascular dementia.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Mild Cognitive Impairment Alzheimer Disease Vascular Dementia

Interventions

Retinal fundus photographyDIAGNOSTIC_TEST

Fundus photographs

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Patients older than 18 years and diagnosed with mild cognitive impairment (MCI), Alzheimer's disease (AD), or vascular cognitive impairment and/or dementia (VaD). Exclusion Criteria: * Children and subjects with other diagnoses than those mentioned in the inclusion criteria. * Patients without the means to visit the clinic on the assigned dates. * Patients who are pregnant or are expecting to become pregnant.

Locations (1)

Mayo Clinic Arizona

Scottsdale, Arizona, United States

Outcomes

Primary Outcomes

retinopathy features identification

The retinal vascular parameters computed using EyeQuant will be compared against the current gold-standard, based on expert annotations

Time frame: 12 months

Data from ClinicalTrials.gov

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