This study will characterize risk factors for poor COVID-19 outcomes (hospitalization, death) and clinical progression of hospitalized COVID-19 patients in South Sudan and Eastern Democratic Republic of the Congo.
A prospective cohort design will be used to follow suspected, probable, and confirmed COVID-19 cases presenting for care at International Medical Corp \[supported\] health facilities in Juba, South Sudan and the Kivus in Eastern Democratic Republic of the Congo (DRC). This research seeks to assess risk factors for poor outcomes and characterize clinical disease progression of COVID-19 cases in resource-poor humanitarian contexts in Africa. Specifically, this study aims to characterize risk factors for poor COVID-19 outcomes, including both co-morbidities with evidence from high income settings, as well as prevalent conditions in humanitarian settings (e.g., acute malnutrition, malaria, HIV) for which data is not yet available. This research also aims to determine how the progression of confirmed COVID-19 cases in resource-poor African settings may differ from other settings where data are available.
Study Type
OBSERVATIONAL
Enrollment
592
Goma General Hospital
Goma, Democratic Republic of the Congo
Bukavu General Hospital
Kinshasa, Democratic Republic of the Congo
Dr John Garang Infectious Diseases Unit
Juba, South Sudan
Hospitalization
Hospitalization due to COVID-19 (proportion of participants hospitalized and risk factors for hospitalization)
Time frame: patients will be followed until asymptomatic or deceased (an average of approximately 1 month)
Mortality
Death due to COVID-19 (proportion of participants deceased and risk factors for death)
Time frame: patients will be followed until asymptomatic or deceased (an average of approximately 1 month)
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