UVA Light Device to Treat COVID-19

Change in Bacterial Load

Change of bacterial load in upper airway

Time frame: 5 days

Ventilated Associated Pneumonia

Percentage of patients developing ventilated pneumonia (VAP) within 30 days of treatment

Time frame: 1 month

Days to Extubation

Number of days patient is intubated with endotracheal tube or tracheostomy

Time frame: 1 month

Days to Discharge

Number of days patient is discharged from the hospital

Time frame: 1 month

Change in C-reactive Protein

Change in C-reactive protein from baseline to the end of the treatment

Time frame: 5 days

Change in the World Health Organization (WHO) Coronavirus Disease (COVID)-19 10-point Ordinal Severity Scale by 30 Days

The World Health Organization (WHO) COVID-19 10-point ordinal severity scale: 0 uninfected, No viral RNA detected 1. Asymptomatic; viral RNA detected 2. Ambulatory Mild disease: Symptomatic; independent 3. Ambulatory Mild disease: Symptomatic; assistance needed 4. Hospitalized: Moderate disease; no oxygen therapy 5. Hospitalized: Moderate disease; oxygen by mask or nasal prongs 6. Hospitalized: sever disease, Oxygen by non-invasive ventilation or high flow 7. Hospitalized: severe disease, intubation and mechanical ventilation, pO2/FiO2\>=150 or SpO2/FiO2\>=200 8. Hospitalized: severe disease, Mechanical ventilation pO2/FiO2\<150(SpO2/FiO2 \<200) or vasopressors 9. Hospitalized: severe disease, Mechanical ventilation pO2/FiO2\<150 and vasopressors, dialysis or extracorporeal membrane oxygenation 10. Death