Smoking is associated with a higher rate of surgical complications. For example, in orthopedics, the risk of complications is 31% in smokers against 5% in non-smokers. The management of this addiction is recommended and particularly interesting in scheduled surgery, because it allows smoking cessation well before the procedure. However, for patients who cannot consider this smoking cessation, the mere information of the risk cannot be sufficient and a real strategy must be constructed and evaluated. Currently, studies results indicate that a patient reducing the number of smoked cigarettes will unconsciously modify their smoking behaviour to obtain the usual nicotine level, this effect is called self-titration. Conversely, nicotine replacement while continuing consumption could induce an improvement in smoking behaviour, therefore less intoxication which would be beneficial in terms of reduction of post-operative complications. This study seeks to assess the effectiveness of a systematic proposition of nicotine replacement therapy (NRT) in regular smokers. Tobacco addiction specialists have demonstrated that intoxication and dependence are well correlated with the exhaled carbon monoxide (CO) level, so this measurement will be used in addition to the patient's interview.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
20
Nicotine replacement therapy is proposed to every patient included in the study. Whether the patient accepts the therapy or not, exhaled carbon monoxide is measured at the preoperative consultation (about 15 days before surgery) and the day of surgery by a nurse. These two measures are compared to assess efficacy of nicotine replacement therapy.
Groupe hospitalier Mutualiste de Grenoble
Grenoble, France
Efficacy of a systematic proposition of nicotine replacement therapy, regardless of the intention to quit Change in exhaled carbon monoxide level between the two measurements, assessed by a carbon monoxide breath monitor
Time frame: At inclusion, and before surgery
Number of patients who refuse nicotine replacement therapy
Time frame: At inclusion
Effect of nicotine replacement therapy on the type of analgesics administrated
Time frame: At inclusion, before surgery, and 2 days after surgery
Effect of nicotine replacement therapy on the duration of analgesics administrated
Time frame: At inclusion, before surgery, and 2 days after surgery
Effect of nicotine replacement therapy on the dose of analgesics administrated
Time frame: At inclusion, before surgery, and 2 days after surgery
Number of smoking cessations
Time frame: 2 days after surgery
Efficacy of a systematic proposition of nicotine replacement therapy, depending on the intention to quit Change in exhaled carbon monoxide level between the two measurements, assessed by a carbon monoxide breath monitor
Subgroup analysis of the primary endpoint according to predefined groups
Time frame: At inclusion, and before surgery
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