The purpose of this study is to investigate whether it is feasible to implement pharmacogenetic testing as part of medication review while the patient is admitted to hospital.
Earlier studies have shown that pharmacogenetic testing may contribute to optimizing the efficacy of medication treatment and to reduce the risk of adverse effects. Inclusion of pharmacogenetic testing as part of medication reviews reveals more serious drug related problems and leads to more changes in medication treatment than medication review alone. The use of pharmacogenetic testing as part of medication reviews has not earlier been systematically investigated in hospital patients in Norway. There is little documentation of what is needed to implement the use of pharmacogenetic testing in a hospital ward. The investigators are conducting a descriptive study in two internal medicine wards at Akershus University Hospital. 50 patients using minimum 5 regular drugs including at least one relevant for pharmacogenetic testing will be enrolled in the study.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
46
genotyping for genes that affect drug metabolism
systematic and interdisciplinary method aiming to increase quality of medication treatment
Akershus University Hospital
Lørenskog, Nordbyhagen, Norway
Number of patients with results from pharmacogenetic testing included in medication review
Number of patients
Time frame: from admission to discharge, an average of 1 week
Acceptance of recommendations
Degree of acceptance of recommendations after pharmacogenetic testing, by prescribers
Time frame: after medication review and before discharge, an average of 3 days
Documentation of information from pharmacogenetic testing
Number of patients with information from pharmacogenetic testing documented in the patient journal
Time frame: after medication review and before discharge, an average of 3 days
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