TREATMENT WITH ANTI-SARS-COV-2 IMMUNOGLOBULIN IN PATIENTS WITH COVID-19

Inclusion Criteria: * Inpatients diagnosed with COVID-19 by RT-PCR; * Time between symptom onset and inclusion ≤ 10 days; * Age ≥ 18 years and \<75 years * No indication of invasive ventilatory support at the time of randomization; * Signature of the Informed Consent Form. Exclusion Criteria: * Pregnant or lactating women * Severe comorbidity: Severe heart disease, severe COPD or O2-dependent COPD, terminal cancer. * Any confirmed or suspected immunosuppressive or immunodeficiency state, including HIV (regardless of treatment, CD4 count or viral load status); asplenia; severe recurrent infections and chronic use (more than 14 days) of immunosuppressive medication in the last 6 months, except for topical steroids or short-term oral steroids (cycle lasting ≤14 days); * History of anaphylaxis or severe allergic reaction; * Previous use of any heterologous serum; * Participation in trials of prophylactic drugs or vaccines for COVID-19; * Administration of immunoglobulins and / or any blood products in the previous three months.