MSSA and MRSA Screening in Patients Undergoing Elective TJA: the Benefits of Next-generation Sequencing

Rothman Institute Orthopaedics163 enrolled

Overview

The aims of this study were to evaluate the diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques and to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients

Study Type

OBSERVATIONAL

Enrollment

163

Conditions

Staphylococcus Aureus Next Generation Sequencing Total Joint Arthroplasty

Interventions

next generation sequencingDIAGNOSTIC_TEST

diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques on S. aureus detection in orthopaedic patients

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All patients undergoing primary total knee or total hip arthroplasty at our institution will be eligible. Exclusion Criteria: * Patients included in other prospective studies

Locations (1)

Rothman Orthopaedic Institute

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Diagnostic techniques to identify S. aureus in total joint replacement patients

to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients.

Time frame: 1 day

Data from ClinicalTrials.gov

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