Serratus Anterior Block and Erector Spinae Block in Postoperative Analgesia

National Cancer Institute, Egypt90 enrolled

Overview

90 patients scheduled for thoracic cancer surgeries, allocated in 3 groups for serratus anterior block and erector spinae block and control group. during anaesthesia:total intraoperative fentanyl required will be recorded. After surgery, all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded.

90 patients scheduled for thoracic cancer surgeries, allocated in 3 groups for serratus anterior block (SAB) and erector spinae block (ESB) and control group. During anaesthesia: total intraoperative fentanyl required will be recorded. After surgery, all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded. Other secondary outcomes are: numerical rating scales and postoperative pulmonary functions.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

QUADRUPLE

Enrollment

Conditions

Postoperative Analgesia

Interventions

Serratus anterior block (SAB)PROCEDURE

Patients will receive a sonar guided serratus anterior plane block with 20 ml of bupivacaine 0.5%

Erector spinae blockPROCEDURE

Patients will receive a sonar-guided erector spinae plane block with 20 ml of bupivacaine 0.5%

Saline (as a placebo)DRUG

Patients will receive a sham block with 20 ml saline (as a placebo)

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with class II physical status (American Society of Anaesthesiologists) , * Age between 18-70 years, * Scheduled for thoracic cancer surgery Exclusion Criteria: * Patient refusal. * Local infection at the site of the block. * Cardiac dysfunction (ejection fraction \<45%). * Significant respiratory disorders. * Preexisting neurological or psychiatric disease. * Allergy to one of the study drugs. * Pregnancy. * Coagulopathy

Locations (1)

National Cancer Institute

Cairo, Egypt

Outcomes

Primary Outcomes

total morphine consumption in first postoperative 24 hours

the amount of morphine required to relieve pain will be recorded

Time frame: first 24 postoperative hours

Secondary Outcomes

intraoperative fentanyl requirement

the amount of fentanyl required during anaesthesia will be recorded

Time frame: during anaesthesia

numerical rating scale

numerical rating scale (from 0 to 10, where 0 represents no pain and 10 represents the worst imaginable pain) will be recorded in different time intervals during the first 24 hours after surgery

Time frame: the first 24 postoperative hours

pulmonary functions

FVC and FEV1 will be recorded at 24 hours after surgery

Time frame: 24 hours after surgery

Data from ClinicalTrials.gov

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