the study is designed to compare the effect of addition of oral Ivabradine, propranolol to general anesthesia aimed reduction in blood loss during functional endoscopic sinus surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
60
Ivabradine group will receive ivabradine 5mg PO in the evening and 1 hour before anesthetic induction
propranolol group will receive propranolol 10 mg PO in the evening and 1 hour before anesthetic induction.
Ahmed Talaat Ahmed
Asyut, Egypt
RECRUITINGchange in blood loss
Estimated blood loss in millilitres per hour is calculated by subtracting the volume of total irrigation used during the case from the total amount of fluid in the suction canister at the end of surgery in addition, pre-weighing and post-weighing of sponges and oropharyngeal packs were also done and dividing by surgical time in hours. assessment of blood loss by Boezaart and van der Merwe Grading System for bleeding during Endoscopic Sinus Surgery
Time frame: immediately after the surgery
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