Utility of Single-dose Oral Antibiotic Prophylaxis in Prevention of Surgical Site Infection in Dermatologic Surgery

Inclusion Criteria: * 18 years of age or older * presenting to Carilion Clinic Dermatology and Mohs surgery in Roanoke, VA at Riverside 1 * suspected to undergo a single-staged repair including a skin flap or graft on the nose * OR suspected to undergo single-staged repair including a skin graft or flap or wedge resection 1 on the ear * OR undergoing Mohs with closure or partial closure or surgical excision on the lower extremity below the knee Exclusion Criteria: * patients with intellectual or mental impairment affecting ability to give informed consent * use of any antibiotic (other than intervention) within 48 hours of the surgery suspected infection at time of surgery * inability to take cephalexin or clindamycin hydrochloride due to allergy or intolerance current inflammatory skin disease affecting the surgical site * Patients undergoing concurrent surgery to oral or nasal mucosa * Patients who have had a recent prosthetic joint surgery within two years and have been told they require antibiotic prophylaxis. * Patients who are currently pregnant, concerned they could be pregnant, actively trying to conceive, or missed last menstrual period that is not explainable by a birth control method.