The study is being conducted to evaluate the efficacy and safety of SHR-1701 with or without chemotherapy in the treatment of unresectable stage III non-small cell lung cancer
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
107
Drug: SHR-1701 30mg/kg Drug: Paclitaxel 175mg/m2 Drug: Carboplatin AUC 5
Drug: SHR-1701 30mg/kg
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China
ORR
Objective response rate
Time frame: From the initiation of the first dose to 3 years
EFS
event free survival
Time frame: From the initiation of the first dose to 3 years
OS
overall survival
Time frame: From the initiation of the first dose to 3 years
EFS rate
event free survival rate
Time frame: From the initiation of the first dose to 3 years
TDDM
time to death or distant metastasis
Time frame: From the initiation of the first dose to 3 years
Adverse events(AEs)
Incidence of treatment-related AEs
Time frame: From the initiation of the first dose to 90 days after the last dose
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