Comparison Between Two Revascularization Strategies in MVD Patients With Uncomplicated ST-elevation MI

Inclusion Criteria: 1. Men and women with successful PCI (preferably using a drug-eluting stent) to the culprit lesion for STEMI ( PCI for STEMI should be primary PCI in the first 12 hours after symptom onset) and complete revascularization of non-culprit lesions during the index PPCI procedure or during a different procedure performed before index hospital discharge. 2. Multi-vessel disease defined as at least 1 additional non-infarct related coronary artery lesion that is at least 2.5 mm in diameter that has not been stented as part of the primary PCI and that is amenable to successful treatment with PCI and has: * At least 75% diameter stenosis (visual estimation) or * At least 50% diameter stenosis (visual estimation) with fractional flow reserve (FFR) ≤ 0.80 3. Age between 18 and 90 years 4. Written informed consent could be obtained from all the patients Exclusion Criteria: 1. Rescue PCI for failed fibrinolysis or a combination strategy where PCI is performed routinely 3-12 hours after fibrinolysis 2. Cardiogenic shock 3. Non-cardiovascular known co-morbidity reducing life expectancy to \< 2 years 4. Any factor precluding 1year follow-up 5. Prior Coronary Artery Bypass Graft (CABG) Surgery 6. A different operator from the previously designated 7. Unable to provide consent for any other reason