Polyethylene glycol (PEG) is one of the most common laxatives used in colonoscopy. However, 5 - 15% of patients can not complete the preparation due to its poor taste and large volume. So this study is aimed to explore the effect of antiemetics on abdominal discomforts associated with PEG.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
200
Domperidone and sulpiride are antiemetics that may be useful in preventing the PEG-related nausea and vomiting.
Domperidone and sulpiride are antiemetics that may be useful in preventing the PEG-related nausea and vomiting.
Shengliang Chen
Shanghai, China
RECRUITINGIncidence of the discomforts during bowel preparation
The primary endpoint of this study was the discomforts during bowel preparation such as nausea, vomit, abdominal fullness and pain. These symptoms were assessed as none, mild, moderate and severe. Patients with mild to severe symptoms were classified as presence of discomforts.
Time frame: before colonoscopy
The quality of bowel preparation assessed by Boston Bowel Preparation Scale
The secondary endpoint was the quality of bowel preparation assessed by the Boston Bowel Preparation Scale (BBPS) during the withdrawal phase of colonoscopy. The BBPS uses a 0-3 points scale assessing the bowel preparation quality in 3 segments of the colon (the right, transverse and left colons). BBPS score ≥ 6 were defined as adequate bowel preparation.
Time frame: during colonoscopy
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