The study investigators hypothesize that Clostridium butyricum and Clostridium neonatal will be more frequently found in the stool of preterm infants with ulcerative necrotizing enterocolitis compared to healthy matched control infants. Systematic daily samples should show that the kinetics of colonization precedes the onset of the pathology. Finally, the systematic ecological survey at the time of infection could help understand the mode of acquisition and transmission of these bacteria.
Study Type
OBSERVATIONAL
Enrollment
40
Stools samples taken daily to test for present of Clostridium butyricum and Clostridium neonatale
CHU de Nimes
Nîmes, France
Presence of C. butyricum
PCR
Time frame: Each day of hospitalization (maximum 120 days)
Presence of C. neonatale
PCR
Time frame: Each day of hospitalization (maximum 120 days)
Culture of C. butyricum
Growth on selective media
Time frame: Each day of hospitalization (maximum 120 days)
Culture of C. neonatale
Growth on selective media
Time frame: Each day of hospitalization (maximum 120 days)
Localisation within the hospital
Bed numbers occupied
Time frame: During hospitalization (maximum 120 days)
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