Factors Associated With CPC 1-2 in 110 Patients Admitted in French ICU for a Myocardial Infarction Complicated by an OHCA.

Central Hospital, Nancy, France110 enrolled

Overview

This study evaluate the association of some in-ICU factors with the neurological prognosis of patients admitted for an out-of-hospital cardiac arrest due to a myocardial infarction.

Pre-hospital factors associated with poor neurologic outcome are well known. Meanwhile, in-ICU factors for the first 24 hours may impact neurologic outcome. This observational study aim to study the factors such as ECLS, NSE dosage, therapeutic hypotermia... and their association with neurologic outcome in patient with myocardial infarction due to instable coronaropathy complicated by an out-of-+hospital cardiac arrest. This is designed to be a observationnal, prospective, multicentric national french study

Study Type

OBSERVATIONAL

Enrollment

110

Conditions

Out-Of-Hospital Cardiac Arrest Myocardial Infarction Coma Outcome, Fatal Neurologic Dysfunction

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * aged of 18 years old or more * non opposition of the patient, or his family if he is unable to consent, after loyal and comprehensive explanation * patient admitted in ICU * the reason for admission is a resurected out-of-hospital cardiac arrest * the cause of the cardiac arrest is a type 1 myocardial infarction Exclusion Criteria: * refractory cardiac arrest (no flow \> 30 minutes in normothermia) * in-hospital cardiac arrest * pregnancy * patient under juridic protection * opposition of the patient, or of his family is he is unable to consent.

Outcomes

Primary Outcomes

Neurologic outcome (CPC)

Cerebral Performance Category Scale to assess neurologic outcome 1-2 : good outcome 3-4-5 : bad outcome

Time frame: 30 day from in-ICU admission

Secondary Outcomes

Neurologic outcome (Rankin)

Rankin score to assess neurologic outcome * 0-1-2 good outcome * 3-4-5 bad outcome

Time frame: 30 day from in-ICU admission

death

all-causes death

Time frame: 30 day form in-ICU admission

Central Contacts

BRUNO LEVY, MD-PHD

CONTACT

03 83 15 40 84 b.levy@chru-nancy.fr

Data from ClinicalTrials.gov

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