Multicenter cohort study of individuals reporting behavioral risks of HIV acquisition, recruited among those presenting for testing for HIV and other sexually transmitted infections. Overarching goal: to study factors associated with uptake of HIV prevention and (re)testing services in medium-sized cities in Thailand. Primary objective: To estimate the incidence of HIV and other sexually transmitted infections (syphilis, chronic hepatitis B and C) among individuals presenting for retesting. Secondary objectives: * To evaluate the uptake of pre-exposure prophylaxis * To assess retention in the study * To evaluate client HIV knowledge * To describe HIV prevalence and characteristics of individuals newly diagnosed with HIV * To describe characteristics of individuals at risk of HIV infection * To assess the quality of the testing and referral services.
Testing and counseling for HIV, syphilis and other sexually transmitted infections is provided to consenting individuals. Components: interactive counseling program, self sampling (finger prick) under supervision, questionnaire (on a tablet computer) to assess risks of HIV acquisition, understanding of HIV transmission routes and pre-exposure prophylaxis, willingness to take pre-exposure prophylaxis if at risk of HIV, and satisfaction with regard to services provided. Referral to appropriate care facility of participants diagnosed with infection. HIV negative participants with significant risk of HIV are advised to come back for HIV retesting within 3 to 6 months and informed about pre-exposure prophylaxis.
Study Type
OBSERVATIONAL
Enrollment
3,000
STIs Clinic of the Office of Disease Prevention and Control Region 1
Chiang Mai, Thailand
RECRUITINGClinical Service Center, Faculty of Associated Medical Sciences, Chiang Mai University
Chiang Mai, Thailand
RECRUITINGMAP Foundation
Chiang Mai, Thailand
RECRUITINGChiang Rai Obstetrics Clinic
Chiang Rai, Thailand
RECRUITINGPhayao Hospital
Phayao, Thailand
NOT_YET_RECRUITINGUniversity of Phayao Medical Center and Hospital
Phayao, Thailand
RECRUITINGHIV incidence
HIV incidence
Time frame: Through study completion, an average of 3 years
Participants initiating pre-exposure prophylaxis
Proportion of participants initiating pre-exposure prophylaxis among those at significant risk of HIV
Time frame: Through study completion, an average of 3 years
Retention
Cumulative probability of retest
Time frame: Through study completion, an average of 3 years
HIV knowledge
Answers to a self-constructed questionnaire assessing participants' knowledge of HIV transmission routes and pre-exposure prophylaxis, following counseling. The questionnaire is composed of one multiple-choice question on HIV transmission routes and three True/False questions on pre-exposure prophylaxis. The results will be reported item by item. Exploratory data analyses may be conducted using, for example, principal component analysis.
Time frame: Through study completion, an average of 3 years
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