Purpose: The purpose of this article is to examine the clinical application of PRP and PRP+hyaluronic acid in disorders in the knee. Methods: The study was conducted on 150 adult patients with age over 20 years old affected by unilateral ACL complete tear and receiving ACL reconstruction. We divided the patients in three groups, and we treated the group A with perioperative injection of HHA, group B with perioperative HHA+PRP, group C with perioperative normal saline. Follow-up: Every 1,3,and 12months, we recheck physical exmianation at OPD and recheck MRI at postoperative 3 months.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
150
PRP preparations also improved functional outcome scores compared to hyaluronic acid and placebo in patients affected by knee osteoarthritis (OA). Based on previous studys, we can conclude that the PRP treatment is a safe and efficacious procedure which can provide functional benefit.
Few studies investigated the effects of HA+PRP combined treatment for knee osteoarthritis (OA). Numerous studies demonstrated the efficacy of HA injection therapy in knee OA for a clinical point of view, reducing the pain and improving the quality of life.
In this study, we compare introperative PRP/PRP+HA/normal saline in ACL reconstruction patient.
Kaohsiung Veterans General Hospital
Kaohsiung City, Kaohsiung, Taiwan
RECRUITING150 of participants with preoperative and postoperative physical examination are accessed by anterior drawer test and Lachman test
the investigators recheck physical exmianation of participants at OPD; physical examination was checked by one orthopedist
Time frame: postoperative 1 month
150 of participants with preoperative and postoperative physical examination are accessed by anterior drawer test and Lachman test
the investigators recheck physical exmianation of participants at OPD; physical examination was checked by one orthopedist
Time frame: postoperative 3 months
150 of participants with preoperative and postoperative physical examination are accessed by anterior drawer test and Lachman test
the investigators recheck physical exmianation of participants at OPD; physical examination was checked by one orthopedist
Time frame: postoperative 12 months
150 of participants with preoperative and postoperative Magnetic Resonance Imaging are accessed
anterior cruciate ligament was accessed by MRI T1 and T2 image; MRI was checked by one orthopedist
Time frame: postoperative 3 month
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