Stress Cardiac MRI in Ischemic Patients

Assiut University50 enrolled

Overview

The aim of this study is to assess the diagnostic accuracy of CMR feature-tracking (FT) at rest \& during stress with low dose dobutamine (LDD) in the evaluation of viability in ischemic cardiomyopathy (ICM) patients and compare it with delayed gadolinium enhancement (DGE).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Ischemic Cardiomyopathy

Interventions

MRIDIAGNOSTIC_TEST

the patients will underwent dobutamine stress cardiac MRI

Eligibility

Sex: ALLMin age: 20 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All patients recruited into the study have chronic LV systolic dysfunction due to coronary artery disease (CAD) Exclusion Criteria: * All patients with a contraindication to MR study: * Patients with implanted non-MRI compatible electronic devices (e.g. Cardiac pacemakers, intracranial metallic clips, implanted hearing aids, etc.) * Patients with foreign bodies in the eye. * Claustrophobic patients. * Patients diagnosed with recent acute coronary syndrome within 4 weeks. * Patients who had contraindications for MRI or contrast agents, and those with poor image quality due to either inadequate breath holding or arrhythmias

Outcomes

Primary Outcomes

comparison of myocardial strain with late gadolinium enhancement

analysis of the myocardial strain by low dose dobutamine and test if it can assess myocardial viability

Time frame: Baseline

Central Contacts

Abdulrahman Hamdan

CONTACT

1005363950 abdulrahman.emam@med.au.edu.eg

Data from ClinicalTrials.gov

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